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Lewis & Clark AgriFood
Lewis & Clark AgriFood

Downstream Processing Engineer II



Seattle, WA, USA
Posted on Saturday, March 11, 2023

Located in Seattle, Washington, Arzeda is solving some of today’s hardest and most meaningful problems – from food and nutrition to sustainable materials and homecare – by designing proteins that have the limitless potential to change everyone’s daily life. Our Intelligent Protein Design Technology™ merges computational protein design, machine learning, and synthetic biology tools to produce proteins, enzymes, and bio-based processes more efficiently than even Mother Nature. A deep tech, mission-driven company, we are passionate about our mission to design novel proteins and products that enhance our lives and protect our planet. At Arzeda, we value a strong desire to learn, innovate and be continuously challenged.

We are seeking an experienced Downstream Processing Engineer II to join our growing DSP team. In this role, you will leverage your fermentation and DSP expertise to develop and optimize our in-house processing capabilities as well as be a liaison to our CMO partners and clients for tech transfer and scale up. Additionally, you will serve as a technical SME within downstream processing and assist in the mentorship of junior engineers. If you are seeking a role where you can demonstrate your engineering know-how, we’d love to speak with you!


  • Develop and optimize manufacturing processes for enzyme and bioconversion systems.
  • Scale up processes from lab to pilot to commercial scale.
  • Provide technical guidance in designing, planning, and implementing experiments.
  • Experience with downstream recovery of material; specifically, solid recovery, crystallization, evaporation, centrifugation, etc.
  • Develop tech transfer documentation including process flow diagrams, material balances, cost analysis.
  • Provide technical support for development and production trials at CMOs, partners.
  • Develop and implement safety procedures and foster safe lab practice.


  • BS degree in chemical, biochemical, manufacturing, food engineering or similar.
  • Five years of industry experience in biochemical/chemical research and development, pilot plant, or manufacturing environments.
  • Two to three years of experience providing technical mentorship to junior scientists/engineers.
  • Two to three years of experience with equipment implementation (sourcing, purchasing, installation).
  • Ability to travel 20% of the time to support development and production trials.

Nice-to-haves (but not required):

  • MS degree in chemical, biochemical, manufacturing, food engineering or similar.
  • Six to ten years of industry experience in biochemical/chemical research and development, pilot plant, or manufacturing environments.
  • Experience with industrial equipment implementation in a pilot plant or manufacturing setting.
  • Experience with equipment design.
  • Process and cost modeling and computer simulation experience.

Arzeda compensation and benefits include:

  • Comprehensive compensation package, to include equity
  • Base Salary: $100,000-130,000 (may vary based on level of experience, education and geography)
  • Paid time off; company-observed holidays to include a company paid holiday closure between Dec 25 and Jan 1; and paid medical/family leave
  • Excellent medical, dental, and vision insurance to include options for Health Savings Accounts
  • 401(k) retirement savings plan
  • Commuter benefits

Arzeda is an equal opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.

Legal authorization to work in the United States is required. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.